Archives 2013

2013

The LXR/RXR Approaches in Alzheimer’s Disease: Is the Blood-Brain Barrier the Forgotten Partner?

Saint-Pol J, Candela P, Fenart L, Gosselet F.

J Alzheimers Dis Parkinsonism 2013, 3:e130

Lien vers le site du journal.

 

Accelerated Caco-2 cell permeability model for drug discovery.

Sevin E, Dehouck L, Lundquist S, Dehouck MP, Cecchelli R, Culot M.

J Pharmacol Toxicol Methods. 2013 Nov-Dec;68(3):334-9. doi: 10.1016/j.vascn.2013.07.004. Epub 2013 Aug 3.

Lien vers l'article:  23916595

 

A simple method for assessing free brain/free plasma ratios using an in vitro model of the blood brain barrier. 

Culot M, Fabulas - da Costa A, Sevin E, Szorath E, Martinsson S, Renftel M, Hongmei Y, Cecchelli R, Lundquist S.

PLoS ONE. 2013 Dec 3;8(12):e80634. doi: 10.1371/journal.pone.0080634. eCollection 2013.

Lien vers l'article: 24312489

 

In vitro blood-brain barrier model adapted to repeated-dose toxicological screening.

Fabulas - da Costa A, Aijjou R, Hachani J, Landry C, Cecchelli R, Culot M.

Toxicol In Vitro , 2013 Sep;27(6):1944-53. doi: 10.1016/j.tiv.2013.06.026. Epub 2013 Jul 9.

Lien vers l'article:  23850739

 

Amyloid-β peptides, Alzheimer's disease and the blood-brain barrier.

Gosselet F, Saint-Pol J, Candela P, Fenart L.

Current Alzheimer Research. 2013 Dec;10(10):1015-33.

Lien vers l'article:  24156262

 

Prevention of rt-PA induced blood-brain barrier component degradation by the poly(ADP-ribose)polymerase inhibitor PJ34 after ischemic stroke in mice.

Teng F, Beray-Berthat V, Coqueran B, Lesbats C, Kuntz M, Palmier B, Garraud M, Bedfert C, Slane N, Bérézowski V, Szeremeta F, Hachani J, Scherman D, Plotkine M, Doan BT, Marchand-Leroux C, Margaill I.

Exp Neurol, 2013 Oct;248:416-28..

Lien vers l'article:  23876515

 

Diesel exhaust particles impair endothelial progenitor cells, compromise endothelial integrity, reduce neoangiogenesis, and increase atherogenesis in mice.

Pöss J, Lorenz D, Werner C, Pavlikova V, Gensch C, Speer T, Alessandrini F, Berezowski V, Kuntz M, Mempel M, Endres M, Böhm M, Laufs U.

Cardiovasc Toxicol. 2013 Sep;13(3):290-300. 

Lien vers l'article : 23584878

 

Endothelial calcium dynamics; connexin channels and blood brain barrier function.

De Bock M, Wang N, Decrock E, Bol M, Gadicherla AK, Culot M, Cecchelli R, Bultynck G, Leybaert L.

Prog Neurobiol, 2013 Jul 9. pii: S0301-0082(13)00050-6. doi: 10.1016/j.pneurobio.2013.06.001. [Epub ahead of print].

Lien vers l'article:  23851106

 

The value of selected in vitro and in silico methods to predict acute oral toxicity in a regulatory context: results from the European Project ACuteTox.

Prieto P, Kinsner-Ovaskainen A, Stanzel S, Albella B, Artursson P, Campillo N, Cecchelli R, Cerrato L, Díaz L, Di Consiglio E, Guerra A, Gombau L, Herrera G, Honegger P, Landry C, O'Connor JE, Páez JA, Quintas G, Svensson R, Turco L, Zurich MG, Zurbano MJ, Kopp-Schneider A.

Toxicol In Vitro, 2013 Jun;27(4):1357-76. doi: 10.1016/j.tiv.2012.07.013. Epub 2012 Aug 16.

Lien vers l'article:  22922246

 

Oxysterols decrease apical-to-basolateral transport of Aß peptides via an ABCB1-mediated process in an in vitro Blood-brain barrier model constituted of bovine brain capillary endothelial cells.

Saint-Pol J, Candela P, Boucau MC, Fenart L, Gosselet F..

Brain Res., 2013 Jun 23;1517:1-15.

Lien vers l'article:  23603412

 

Identification of additional proteins in differential proteomics using protein interaction networks.

Gwinner F, Acosta-Martin A, Boytard L, Chwastyniak M, Beseme O, Drobecq H, Duban-Deweer S, Juthier F, Jude B, Amouyel P, Pinet F, Schwikowski B.

Proteomics, 2013 Apr;13(7):1065-76. doi: 10.1002/pmic.201200482.

Lien vers l'article:  23386401

 

Glial-cell-mediated re-induction of the blood-brain barrier phenotype in brain capillary endothelial cells: a differential gel electrophoresis study.

Deracinois B, Pottiez G, Chafey P, Teerlink T, Camoin L, Davids M, Broussard C, Couraud PO, Dehouck MP, Cecchelli R, Karamanos Y, Flahaut F.

Proteomics, 2013 Apr;13(7):1185-99. doi: 10.1002/pmic.201200166.

Lien vers l'article:  23436736

 

The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury.

Enzmann G, Mysiorek C, Gorina R, Cheng YJ, Ghavampour S, Hannocks MJ, Prinz V, Dirnagl U, Endres M, Prinz M, Beschorner R, Harter PN, Mittelbronn M, Engelhardt B, Sorokin L.

Acta Neuropathol, 2013 Mar;125(3):395-412. doi: 10.1007/s00401-012-1076-3. Epub 2012 Dec 27..

Lien vers l'article:  23269317

 

Truncated Thioredoxin (Trx-80) promotes pro-inflammatory macrophages of the M1 phenotype and enhances atherosclerosis.

Mahmood D, Abderrazak A, Couchie D, Lunov O, Diderot V, Syrovets T, Slimane M-N, Gosselet F, Rouis M, Simmet T, El Hadri K..

J Cell Physiol, 2013 Jul;228(7):1577-83. doi: 10.1002/jcp.24319.

Lien vers l'article:  23335265

 

Time-induced progressive alteration of kir current in cerebral smooth muscle cells of stroke-prone spontaneously hypertensive rats.

Bastide M, Ouk T, Pétrault O, Bordet R.

Int J Hypertens, 2013;2013:849750. doi: 10.1155/2013/849750. Epub 2013 Apr 23.

Lien vers l'article:  23710341