A snapshot on the progress of in vitro toxicology for safety assessment.
Jennings P, Corvi R, Culot M.
Toxicol In Vitro. 2017 Dec;45(Pt 3):269-271. doi: 10.1016/j.tiv.2017.10.024.
Lien vers article : 29195642
Disease-Induced Alterations in Brain Drug Transporters in Animal Models of Alzheimer's Disease.
Vellonen KS, Ihalainen J, Boucau MC, Gosselet F, Picardat T, Gynther M, Kanninen KM, White AR, Malm T, Koistinaho J, Forsberg MM, Ruponen M.
Pharm Res. 2017 Sep 26.
Lien vers article: 28952054
Topical intestinal aminoimidazole agonists of G-Protein-Coupled Bile Acid Receptor 1 promote Glucagon Like Peptide-1 secretion and improve glucose tolerance.
Lasalle M, Hoguet V, Hennuyer N, Leroux F, Piveteau C, Belloy L, Lestavel S, Vallez E, Dorchies E, Duplan I, Sevin E, Culot M, Gosselet F, Boulahjar R, Herledan A, Staels B, Deprez B, Tailleux A, Charton J.
J Med Chem, 2017 Apr 17. doi: 10.1021/acs.jmedchem.6b01873.
Lien vers article: 28414465
Modelling of the blood-brain barrier.
Gosselet, F.
Med Sci (Paris). 2017 Apr;33(4):423-431.
Lien vers article: 28497739
ALCAM (CD166) is involved in extravasation of monocytes rather than T cells across the blood-brain barrier.
Lyck, R, Lécuyer MA, Abadier M, Wyss C, Matti C, Rosito M, Enzmann G, Zeis T, Michel L, García Ana, Sallusto F, Gosselet F, Deutsch U, Weiner J, Schaeren-Wiemers, Prat A, Engelhardt B.
Journal of Cerebral Blood Flow and metabolism. 2016 Nov 14:271678X16678639.
Lien vers article: 28273717
Resveratrol and Grape's Extract-Loaded Solid Nanoparticles for the Treatment of Alzheimer's disease
Loureiro JA, Andrade S, Duarte A, Neves AR, Queiroz JF, Nunes C, Sevin E, Fenart L, Gosselet F, Coelho MAN, Carmo Pereira MD.
Molecules. 2017 Feb 13;22(2).
Lien vers article: 28208831
