BrainBike peptidomimetic enables efficient transport of proteins across brain endothelium.
Lucana MC, Lucchi R, Gosselet F, Díaz-Perlas C, Oller-Salvia B.
RSC Chem Biol. 2023 Dec 11;5(1):7-11.
PMID: 38179197
DOI: 10.1039/d3cb00194f.
Vesicular Trafficking, a Mechanism Controlled by Cascade Activation of Rab Proteins: Focus on Rab27.
Menaceur C, Dusailly O, Gosselet F, Fenart L, Saint-Pol J.
Biology (Basel). 2023 Dec 15;12(12):1530.
PMID: 38132356
25-hydroxycholesterol in health and diseases.
Nguyen C, Saint-Pol J, Dib S, Pot C, Gosselet F.
J Lipid Res. 2023 Dec 15:100486.
PMID: 38104944
DOI: 10.1016/j.jlr.2023.100486.
ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells.
Cicero J, Trouvilliez S, Palma M, Ternier G, Decoster L, Happernegg E, Barois N, Van Outryve A, Dehouck L, Bourette RP, Adriaenssens E, Lagadec C, Tarhan CM, Collard D, Souguir Z, Vandenhaute E, Maubon G, Sipieter F, Borghi N, Shimizu F, Kanda T, Giacobini P, Gosselet F, Maubon N, Le Bourhis X, Van Seuningen I, Mysiorek C, Toillon RA.
Exp Hematol Oncol. 2023 Dec 10;12(1):104.
PMID: 38072918
DOI: 10.1186/s40164-023-00463-6
The Tetraspanin Tspan8 Associates with Endothelin Converting Enzyme ECE1 and Regulates Its Activity.
Zhu Y, Saint-Pol J, Nguyen V, Rubinstein E, Boucheix C, Greco C.
Cancers (Basel). 2023 Sep 27;15(19):4751.
PMID : 37835445
Discovery, Structure-Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5.
Picon S, Boulahjar R, Hoguet V, Baron M, Duplan I, Vallez E, Hennuyer N, Dumont J, Touche V, Dorchies E, Lasalle M, Descat A, Piveteau C, Biela A, Chaput L, Villoutreix BO, Lipka E, Sevin E, Culot M, Gosselet F, Lestavel S, Roussel P, Deprez-Poulain R, Leroux F, Staels B, Deprez B, Tailleux A, Charton J.
J Med Chem. 2023 Aug 28.
PMID: 37639383
DOI: 10.1021/acs.jmedchem.2c01881
Predicting human neurotoxicity of propylene glycol methyl ether (PGME) by implementing in vitro neurotoxicity results into toxicokinetic modelling.
Reale E, Sandstrom J, Culot M, Hechon J, Wellens S, Heymans M, Tschudi-Monnet F, Vernez D, Hopf NB.
Sci Total Environ. Sci Total Environ. 2023 Aug 15;886:163767.
PMID: 37156387
DOI: 10.1016/j.scitotenv.2023.163767
Differential Blood-Brain Barrier Transport and Cell Uptake of Cyclic Peptides In Vivo and In Vitro.
Melander E, Eriksson C, Wellens S, Hosseini K, Fredriksson R, Gosselet F, Culot M, Göransson U, Hammarlund-Udenaes M, Loryan I.
Pharmaceutics. 2023 May 16;15(5):1507.
PMID: 37242750
DOI: 10.3390/pharmaceutics15051507
Challenges and Opportunities in the Oral Delivery of Recombinant Biologics.
Masloh S, Culot M, Gosselet F, Chevrel A, Scapozza L, Zeisser Labouebe M.
Pharmaceutics. 2023 May 5;15(5):1415.
PMID: 37242657
DOI: 10.3390/pharmaceutics15051415
High levels of endothelial ICAM-1 prohibit natalizumab mediated abrogation of CD4+ T cell arrest on the inflamed BBB under flow in vitro.
Soldati S, Bär A, Vladymyrov M, Glavin D, McGrath JL, Gosselet F, Nishihara H, Goelz S, Engelhardt B.
J Neuroinflammation. 2023 May 23;20(1):123.
PMID: 37221552
DOI: 10.1186/s12974-023-02797-8
Highlighting In Vitro the Role of Brain-like Endothelial Cells on the Maturation and Metabolism of Brain Pericytes by SWATH Proteomics.
Menaceur C, Hachani J, Dib S, Duban-Deweer S, Karamanos Y, Shimizu F, Kanda T, Gosselet F, Fenart L, Saint-Pol J.
Cells. 2023 Mar 25;12(7):1010.
PMID: 37048083
Impact of Pesticide Residues on the Gut-Microbiota-Blood-Brain Barrier Axis: A Narrative Review.
Abou Diwan M, Lahimer M, Bach V, Gosselet F, Khorsi-Cauet H, Candela P.
Int J Mol Sci. 2023 Mar 24;24(7):6147.
PMID: 37047120
DOI: 10.3390/ijms24076147
TNFα Activates the Liver X Receptor Signaling Pathway and Promotes Cholesterol Efflux from Human Brain Pericytes Independently of ABCA1.
Dib S, Loiola RA, Sevin E, Saint-Pol J, Shimizu F, Kanda T, Pahnke J, Gosselet F.
Int J Mol Sci. 2023 Mar 22;24(6):5992.
PMID: 36983062
