Publications

2024

Effects of Chlorpyrifos on gut dysbiosis and barriers integrity in women with a focus on pregnancy and prebiotic intervention: insights from advanced in vitro human models.

Abou Diwan M, Huet A, Poiriez J, Condette CJ, Delanaud S, Sevin E, Corona A, Rhazi L, Depeint F, Ouadid-Ahidouch H, Gosselet F, Bach V, Candela P, Khorsi-Cauet H.

Environ Pollut. 2024 Dec 12:125533.

PMID: 39674256

DOI: 10.1016/j.envpol.2024.125533

Cyclosporin A toxicity on endothelial cells differentiated from induced pluripotent stem cells: Assembling an adverse outcome pathway.

Mazidi Z, Wieser M, Spinu N, Weidinger A, Kozlov AV, Vukovic K, Wellens S, Murphy C, Singh P, Lagares LM, Bobbili MR, Liendl L, Schosserer M, Diendorfer A, Bettelheim D, Eilenberg W, Exner T, Culot M, Jennings P, Wilmes A, Novic M, Benfenati E, Grillari-Voglauer R, Grillari J.

Toxicol In Vitro. 2024 Nov 14:105954.

PMID : 39550010

DOI : 10.1016/j.tiv.2024.105954

Investigation of Lysophospholipids-DHA transport across an in vitro human model of blood brain barrier.

Hachem M, Ali AH, Yildiz I, Landry C, Gosselet F.

Heliyon. 2024 Oct 2;10(19):e38871. eCollection 2024 Oct 15.

PMID : 39421371

DOI :  10.1016/j.heliyon.2024.e38871

Rift Valley fever virus is able to cross the human blood-brain barrier in vitro by direct infection with no deleterious effects.

Quellec J, Piro-Megy C, Cannac M, Nisole S, Marty FH, Gosselet F, Shimizu F, Kanda T, Cêtre-Sossah C, Salinas S.

J Virol. 2024 Sep 30:e0126724.

PMID: 39345143

DOI:  10.1128/jvi.01267-24

Maternal exposure to pesticides induces perturbations in the gut microbiota and blood-brain barrier of dams and the progeny, prevented by a prebiotic.

Abou Diwan M, Djekkoun N, Boucau MC, Corona A, Dehouck L, Biendo M, Gosselet F, Bach V, Candela P, Khorsi-Cauet H.

Environ Sci Pollut Res Int. 2024 Sep 26.

PMID: 39325129

doi: 10.1007/s11356-024-34969-1

Secretome of brain microvascular endothelial cells promotes endothelial barrier tightness and protects against hypoxia-induced vascular leakage.

Loiola RA, Hachani J, Duban-Deweer S, Sevin E, Bugno P, Kowalska A, Rizzi E, Shimizu F, Kanda T, Mysiorek C, Mazurek M, Gosselet F.

Mol Med. 2024 Aug 26;30(1):132.

PMID: 39187765

DOI: 10.1186/s10020-024-00897-6

25-Hydroxycholesterol attenuates tumor necrosis factor alpha-induced blood-brain barrier breakdown in vitro.

Loiola RA, Nguyen C, Dib S, Saint-Pol J, Dehouck L, Sevin E, Naudot M, Landry C, Pahnke J, Pot C, Gosselet F.

Biochim Biophys Acta Mol Basis Dis. 2024 Aug 22:167479.

PMID: 39181516

DOI: 10.1016/j.bbadis.2024.167479

CD31 orchestrates metabolic regulation in autophagy pathways of rheumatoid arthritis.

Cheung KC, Ma J, Wang L, Chen X, Fanti S, Li M, Azevedo LR, Gosselet F, Shen H, Zheng X, Lu A, Jia W.

Pharmacol Res. 2024 Aug 8:107346.

PMID: 39127263

DOI: 10.1016/j.phrs.2024.107346

Enterovirus A71 crosses a human blood-brain barrier model through infected immune cells.

Gaume L, Chabrolles H, Bisseux M, Lopez-Coqueiro I, Dehouck L, Mirand A, Henquell C, Gosselet F, Archimbaud C, Bailly J-L.

Microbiol Spectr. 2024 May 16:e0069024.

doi: 10.1128/spectrum.00690-24.

PMID: 38752731

DOI : 10.1128/spectrum.00690-24

Synergistic induction of blood-brain barrier properties.

Porkoláb G, Mészáros M, Szecskó A, Vigh JP, Walter FR, Figueiredo R, Kálomista I, Hoyk Z, Vizsnyiczai G, Gróf I, Jan JS, Gosselet F, Pirity MK, Vastag M, Hudson N, Campbell M, Veszelka S, Deli MA.

Proc Natl Acad Sci U S A. 2024 May 21;121(21):e2316006121.

PMID: 38748577

DOI: 10.1073/pnas.2316006121.

Evaluation of the impact of iPSC differentiation protocols on transcriptomic signatures.

Chandrasekaran V, Wellens S, Bourguignon A, Djidrovski I, Fransen L, Ghosh S, Mazidi Z, Murphy C, Nunes C, Singh P, Zana M, Armstrong L, Dinnyés A, Grillari J, Grillari-Voglauer R, Leonard MO, Verfaillie C, Wilmes A, Zurich MG, Exner T, Jennings P, Culot M.

Toxicol In Vitro. 2024 Apr 12:105826.

PMID: 38615723

DOI: 10.1016/j.tiv.2024.105826.

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches.

Welsh JA, and MISEV Consortium.

J Extracell Vesicles. 2024 Feb;13(2):e12404.

PMID: 38326288

DOI: 10.1002/jev2.12404.

Enhancing Oral Delivery of Biologics: A Non-Competitive and Cross-Reactive Anti-Leptin Receptor Nanofitin Demonstrates a Gut-Crossing Capacity in an Ex Vivo Porcine Intestinal Model.

Masloh S, Chevrel A, Culot M, Perrocheau A, Kalia YN, Frehel S, Gaussin R, Gosselet F, Huet S, Zeisser Labouebe M, Scapozza L.

Pharmaceutics. 2024 Jan 16;16(1):116.

PMID: 38258126

DOI: 10.3390/pharmaceutics16010116.